2017年4月4日星期二

Oxymetholone


Oxymetholone (INN, USAN, BAN) (brand names Anadrol, Anapolon, others) is a synthetic, orally active anabolic-androgenic steroid (AAS) and 17α-methylated derivative of dihydrotestosterone (DHT) that is marketed in the United States, Europe, and elsewhere in the world. It was first described in a 1959 paper by scientists from Syntex. Its primary clinical applications include treatment of osteoporosis and anaemia, as well as stimulating muscle growth in malnourished or underdeveloped patients. The drug was approved for human use by the FDA. Later, non-steroidal drugs such as epoetin alfa were developed and proven to be more effective as a treatment for anaemia and osteoporosis without the side effects of oxymetholone. The drug remained available despite this and eventually found a new use in treating HIV wasting syndrome.


Presented most commonly as a 50 mg tablet, oxymetholone is one of the strongest androgenic steroids available. Similarly, there is a risk of side effects. Despite very low binding affinity with the androgen receptor, oxymetholone is highly effective in promoting extensive gains in body mass, mostly by greatly improving protein synthesis. For this reason, it is often used by bodybuilders and athletes.

Oxymetholone COA and HPLC:



Ref. Standard

USP28 Standard

Results Of Analysis Tests


Test

Standard

Results Of Analysis

Identification

Requirements Standard

Conform

Solubility


Clearing

Pass

Melting Point


172~180℃

174~179℃

Specific Rotation

+34~ +38°


+36.3°

Loss On Drying

≤1.0%


0.4%


Organic Volatile Impurities

≤850PPM

320PPM

Assay

97.0~103.0%


99.11%


Conclusion

The specification conform with USP28 standard.

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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body


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