2017年7月4日星期二

Diclazuril


Diclazuril (trade name Vecoxan) is a coccidiostat.
 
Introduction:
 
Diclazuril is a  coccidiostat.Usually used for chicken, duck, quail, turkey, goose and rabbit.
CAS NO.: 101831-37-2
Density:1.56g/cm3
Empirical formula:C17H9Cl3N4O2
Appearance: white crystals or crystalline powderChemical name (IUPAC):
2,6-dichloro-alpha-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3h)-yl)benzeneacetonitrile; 
 
 
usage:
 
 Diclazuril is mainly applied to:
(1)Poultry    Diclazuril is good for eimeria,reactor type, toxicity, Brinell and E.maxima ,it is effectively to control the occurrence and death of cecum ball,even make the disease of chicken coccidia oocysts disappear.
 
(2)Rabbit   The effect of control liver coccidiosis and  intestinal coccidiosis when feed rabbit by diclazuril is good.
 

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Abamectin


Abamectin is a widely used insecticide and anthelmintic.
 
Chemistry
 
Abamectin is a mixture of avermectins containing more than 80% avermectin B1a and less than 20% avermectin B1b. These two components, B1a and B1b have very similar biological and toxicological properties. The avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium Streptomyces avermitilis. Abamectin is a natural fermentation product of this bacterium.
 
Use
 
Abamectin is used to control insect and mite pests of a range of agronomic, fruit, vegetable and ornamental crops, and it is used by homeowners for control of fire ants. Abamectin is also used as a veterinary antihelmintic. Resistance to abamectin-based antihelmintics, although a growing problem, is not as common as to other classes of veterinary antihelmintics. The benzoate salt emamectin benzoate is also used as an insecticide.
 
Abamectin
CAS No. : 71751-41-2 (86753-29-9)
Specification :95% TC  
Classification : Insticide,nematicide and acaricide
Packing: 1kg/Alu. Foil bag, 25kg/drum or according to special requirement.
Storage: Keep in cool and dry place,
Shelf Life: 2 years
Application:avermectin is a new class of antibiotics, has a novel structure, livestock dual characteristics
 
The Specification
 
Item
Index
95% TECH
1.8% EC
Appearance
White crystalline powder
Light yellow liquid
A. I. Content, %
95.0 min
1.8 min
Content  B1a, %
90.0 min
**
Loss on Drying, %
2.0 max
**
Heavy Metal, %
0.001 max
**
Water, %
**
3.0 max
pH Value
4.5~7.5
4.5~7.0 
Residue On Ignition, %
0.1 max
**
Arsenic, ppm
2.0 max
**
Emulsion stability
**
Qualified
 

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2017年6月28日星期三

Levothyroxine


Levothyroxine, also known as L-thyroxine, is a manufactured form of the thyroid hormone, thyroxine (T4). It is used to treat thyroid hormone deficiency including the severe form known as myxedema coma. It may also be used to treat and prevent certain types of thyroid tumors. It is not indicated for weight loss. Levothyroxine is taken by mouth or given by injection into a vein. Maximum effect from a specific dose can take up to six weeks to occur.
Side effects from excessive doses include weight loss, trouble tolerating heat, sweating, anxiety, trouble sleeping, tremor, and fast heart rate. Use is not recommended in people who have had a recent heart attack. Use during pregnancy has been found to be safe. It is recommended that dosing be based on regular measurements of TSH and T4 levels in the blood. Much of the effect of levothyroxine is following its conversion to triiodothyronine (T3).
L-Thyroxine (Levothyroxine) T4, 51-48-9
Catelog: APIs, pharmaceutical chemicals; thyroid hormone agent
MF: C15H11I4NO4
MW: 776.87
CAS :51-48-9
EINECS 200-101-1
Melting point 223 centigrade (dec.)
Water solubility insoluble
Assay: 98.0%
Package: 100g, 300g, 500g, 1000g/Aluminum foil bag
Appearance: white acicula crystal, scentless, degenerate case of light.
Usage: Pharmaceutical raw materials promote General organization of metabolic, increased nerve excitability and Physical development; cure Hypothyroidism, Myxedema, and Cretinism, etc.

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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

Methylhexanamine


Methylhexanamine (trade names Forthane, Geranamine) or methylhexamine, commonly known as 1,3-dimethylamylamine (1,3-DMAA) or simply dimethylamylamine (DMAA), is an indirect sympathomimetic drug invented and developed by Eli Lilly and Company and marketed as an inhaled nasal decongestant from 1944 until it was voluntarily withdrawn from the market in 1983.
 
Since 2006 methylhexanamine has been sold extensively under many names as a stimulant or energy-boosting dietary supplement under the claim that it is similar to certain compounds found in geraniums, but its safety has been questioned as a number of adverse events and at least five deaths have been associated with methylhexanamine-containing supplements. It is banned by many sports authorities and governmental agencies.
 
CAS Number:105-41-9
Formulation: white powder
Purity:≥95%.
Application: For chemical research
Transportation: SEA OR AIR
MOQ: 10 Gram
orgin country:China
Package: 1kg/foil bag or according to the customers requirements.
Storage: Store in a cool dry place and keep away from direct strong light
 

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2017年6月27日星期二

Dihydrotestosterone (DHT)


Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as 5α-androstan-17β-ol-3-one, is an endogenous androgen sex steroid and hormone. The enzyme 5α-reductase catalyzes the formation of DHT from testosterone in certain tissues including the prostate gland, seminal vesicles, epididymides, skin, hair follicles, liver, and brain. This enzyme mediates reduction of the C4-5 double bond of testosterone. Relative to testosterone, DHT is considerably more potent as an agonist of the androgen receptor (AR).
Description:
 
Product Name:Stanolone(Dihydrotestosterone)
CAS No: 521-18-6
Alias:Dihydrotestosterone;DHT; Hydrogenation testosterone; 5 A-two hydrogen testosterone
MF: C19H30O2
MW: 290.44
Purity: 99%
Appearance: white crystal powder.
 
Specification:
 
DescriptionWhite Or Practically White Crystalline Powder
Ref. StandardEnterprise Standard
Results Of Analysis Tests
TestsAnalysis StandardResults
Melting Point176~181℃176.5~181℃
Specific Rotation+25°~ +31°+25.9°
Loss On Drying≤0.5%0.36%
Assay≥97%98.1%
ConclusionBe Conform With Enterprise Standard

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Methocarbamol


Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. Under the trade name Robaxin, it is marketed by Actient Pharmaceuticals in the United States and Pfizer in Canada. The mechanism of action of methocarbamol is currently unknown, but may involve the inhibition of carbonic anhydrase. The muscle relaxant effects of methocarbamol are largely attributed to central depressant effects; however, peripheral effects of methocarbamol to prolong muscle refractory period have also been reported.
Metabolism
 
Methocarbamol is the carbamate of guaifenesin, but does not produce guaifenesin as a metabolite, because the carbamate bond is not hydrolyzed metabolically; metabolism is by Phase I ring hydroxylation and O-demethylation, followed by Phase II conjugation. All the major metabolites are unhydrolyzed carbamates.
 
Product name: Methocarbamol
Synonyms: guaiacol glyceryl ether carbamate; 2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate
CAS RN.: 532-03-6
EINECS: 208-524-3
Molecular Weight: 241.2405
Molecular formula: C11H15NO5
InChI=1/C11H15NO5/c12-11(15)17-10-4-2-1-3-9(10)16-6-5-8(14)7-13/h1-4,8,13-14H,5-7H2,(H2,12,15)
Refractive index: 1.57
Hazard Symbols: Xn:Harmful
Risk Codes: R22;R42/43;
Safety Description: S36
Apperance : white powder
Means of Transportation: By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect...)
Usage : chemical research
Storage: Store in dry, dark and ventilated place
Package: Barrel or Customize
 
ItemStandardTest Results
IdentificationA.H-NMR:Comply with the structureComplies
B.LC-MS:Comply with the structureComplies
C.The IR spectrum of sample should be identical with that of reference standard;Complies
D.HPLC-ESI-MS
The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.
Complies
Crystallinitymeets the requirements.Complies
Loss on drying≤2.0%0.19%
Heavy metals≤10 ppm<10ppm
Water≤1.0%0.1%
Sulphated ash≤0.5%, determined on 1.0 g.0.009%
Related substancesUnspecified impurities: for each impurity≤0.10%<0.10%
Total Impurity≤0.5%0.18%
Purity≥99.0%99.7%
Assay99.0%~101.0% (anhydrous substance).99.8%
Microbiological Analysis
Total plate count≤1000cfu/gComplies
Yeast and Moulds≤100cfu/gComplies
E. Coli.AbsentNegative
SalmonellaAbsentNegative
S.aureusAbsentNegative
StoragePreserve in well-closed, light-resistant and airtight containers.Complie

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Ketotifen fumarate


Ketotifen is a first-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt with fumaric acid, ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis. In its oral form, it is used to prevent asthma attacks or Anaphylaxis, as well as various mast cell, allergic-type disorders.
 
Uses
 
Ketotifen relieves and prevents eye itchiness and/or irritation associated with most seasonal allergies. It starts working within minutes after administering the drops. The drug has not been studied in children under three.
 
 
[Specifications] 
 
Appearance
White or brownish-yellow, fine, crystalline powder
brownish-yellow
crystalline powder
Solubility
Sparingly solube in water ,slight solube in methanol , very slightly solube in acetonitrile
Conforms
 Identification
A.The IR spectrum is concordant with the Ph.Eur.reference spectrum of Ketotifen fumarate .
Conforms
B.The spot due to fuaric acid in the chromatogram obtained with the test solution is similar in position ,color and intensity to the principal spot in the chromatogram obtained with the reference solution
Conforms
Appearance of solution
The solution is clear and not more intensely coloured than reference solution Y4,BY4,or B4
Conforms
Related substances (HPLC)
Impurity G:NMT 0.2%
0.11%
Unspecified impurity :NMT 0.10%
<Disregard limit 0.05%
Total impurities: NMT 0.5%
0.30%
Loss on drying
NMT 0.5%
0.3%
Sulphated ash
NMT 0.1%
0.04
Residual solvens(GC)
Methanol: NMT 3000 ppm
None detected
Ethanol: NMT 5000 ppm
None detected
Acetone: NMT 5000 ppm
2741 ppm
Tetrahydrofuran: NMT 720 ppm
None detected
Assay
NLT 98.5%& NMT101.0%(dried substance)
99.4%

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