2017年3月9日星期四

17alpha-Acetoxy-6-alpha-methylpregn-4-ene-3,20-dione

Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a manufactured hormone of the progestin type. It is used as birth control and as part of hormone replacement therapy for menopausal symptoms. It is also used to treat endometriosis, abnormal uterine bleeding, abnormal sexuality in males, and certain types of cancer. It is used by mouth or injection into a muscle or under the skin

Common side effects include no periods, abdominal pain, headaches, and anxiety. Other serious side effects include bone loss, blood clots, allergic reactions, depression, and liver problems. Use is not recommended during pregnancy as it may harm the baby. It works by decreasing the body's release of gonadotropins.

Medroxyprogesterone acetate was patented and came into medical use in 1958. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.

Product Description
Introduction

Other name: 17alpha-Acetoxy-6-alpha-methylpregn-4-ene-3,20-dione;17a-Hydroxy-6a-methyl-4-pregnene-3,20-dione acetate;Depo-provera
Molecular Formula: C24H34O4
Molecular Weight: 386.52
CAS Registry Number : 71-58-9
EINECS NO.: 200-757-9
InChI: 1S/C24H34O4/c1-14(25)20-7-8-21-19-6-5-16-11-18(27)12-17(13-28-15(2)26)24(16,4)22(19)9-10-23(20,21)3/h11,17,19-22H,5-10,12-13H2,1-4H3/t17?,19-,20+,21-,22-,23+,24+/m0/s1
Melting point: 206-207ºC
Water solubility: <0.1G/100MLAT23ºC
Appearance:White crystalline powder
Specification:99%min
Standard: EP/BP/USP
Odor: odorless

Specification:

ItemSpecification 
IdentificationA:IR   B:UV
Specific optical rotation+45~51°
Chromatographic purityAny individual impurity: ≤1.0%
Total impurities: ≤1.5%
Total related substances≤2.0%
Related compound A≤0.5%
Loss on drying≤1.0%
SterilitySterile
Residual solventsMethanol: ≤3000ppm
Dichloromethane: ≤500ppm
Assay97.0%~103.0%

Packaging & Shipping:

Storage Situation: Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Shelf Life: Two years when properly stored.
Delivery: within two weeks after receiving your prepayment.



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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

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