ethyl apovincaminate

Vinpocetine (brand names: Cavinton, Intelectol; chemical name: ethyl apovincaminate) is a synthetic derivative of the vinca alkaloid vincamine (sometimes described as "a synthetic ethyl ester of apovincamine"), an extract from the lesser periwinkle plant. Vinpocetine was first isolated from the plant in 1975 by the Hungarian chemist Csaba Szántay. The mass production of the synthetic compound was started in 1978 by the Hungarian pharmaceutical company Richter Gedeon.

Vinpocetine is not FDA approved in the United States for therapeutic use. The U.S. Food & Drug Administration (FDA) has ruled that vinpocetine, due to its synthetic nature and proposed therapeutic uses, was ineligible to be marketed as dietary supplement under the Federal Food, Drug, and Cosmetic Act (FDCA).

Vinpocetine has been reported to have cerebral blood-flow enhancing and neuroprotective effects, and has been used as a drug in Eastern Europe for the treatment of cerebrovascular disorders and age-related memory impairment.

Name: Vinpocetine

CAS: 42971-09-5

Quality Standard: USP/BP/EP/JP

Apperance: White crystalline power

Specification

Items	Requirements	Results
Appearance	W  White or slightly yellow, crystalline powder.	Complies
Solubility	Practically insoluble in water, soluble in methylene  chl  chloride, slightly soluble in anhydrous ethanol	Complies
Identification
A. Specific optical ration	Should be positive	Complies
B. Infrared absorption	Should be positive	Complies
C. HPLC	The retention time of the main peak of the sample  solution corresponds to that of the principal peak  for the stock standard solution, as obtained in the  test for organic impurities	Complies
Test
A. Specific optical ration	+ 127 ° to + 134°(dried substance)	+ 132.4°
B. Related substances	Impurity A≤0.6% Impurity B≤0.5% Impurity C≤0.3% Impurity D≤0.5% Any other impurities≤0.1% Total impurities ≤1.0%	0.06% 0.30% 0.06% NA 0.06% 0.48%
C. Loss on drying	≤ 0.5%	0.19%
D. Sulphated ash	≤ 0.1%	0.05%
E. Heavy metals	NMT10ppm	Complies
Assay	98.5%~101.5%	99.4%
Conclusion	The product conforms to EP7

PACKING & SHIPING

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Shipping methods:By Courier, by air or by sea
Packaging: 1kg, 5kg ,25kg or as requested

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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body