2017年3月13日星期一

Emoxypin

Emoxypine (2-ethyl-6-methyl-3-hydroxypyridine), also known as Mexidol or Mexifin when used as the succinate salt, is an antioxidant manufactured in Russia by Pharmasoft Pharmaceuticals. Its chemical structure resembles that of pyridoxine (a type of vitamin B6). It is not approved for any medical use in the United States or Europe.
History

Emoxypine was first synthesized by L.D. Smirnov and K.M. Dumayev, then studied and developed in the Institute of Pharmacology, Russian Academy of Medical Sciences and National Scientific Center of Bioactive Substances Safety.

Use

In Russia, emoxypine has a wide range of applications in medical practice. It purportedly exercises anxiolytic, anti-stress, anti-alcohol, anticonvulsant, nootropic, neuroprotective and anti-inflammatory action. Emoxypine presumably improves cerebral blood circulation, inhibits thrombocyte aggregation, lowers cholesterol levels, has cardioprotective and antiatherosclerotic action.

Emoxypine // Mexidol

Cas 2364-75-2
Chemical name 2-Ethyl-6-methyl-3-pyridinol
MF C8H11NO                          
MW 137.179 g/mol
Melting point 170–172 °C (338–342 °F)
Chemical name  2-Ethyl-6-methyl-3-hydroxypyridine
Synonyms Emoxipine, Emoxypin, Epigid, 6-Methyl-2-ethyl-3-hydroxypyridine
Emoxypine (2-ethyl-6-methyl-3-hydroxypyridine), also known as Mexidol or Mexifin when used as the succinate salt, is an antioxidant manufactured in Russia by Pharmasoft Pharmaceuticals.[2] Its chemical structure resembles that ofpyridoxine (a type of vitamin B6)

Certificate of analysis of our Mexidol Base

TEST
SPECIFICATIONS
RESULTS
Appearance
White to off-white crystalline powder
White crystalline powder
Solubility
Almost insolute in water,solute in alcohol 95%
Conforms
Identification
IR
Should meet the requirement
Conforms
HPLC
Should meet the requirement
Conforms
Melting point
167-170℃
168-170℃
Total impurity
≤1.0%
0.073%
Max single impurity
≤0.1%
0.045%
Loss on drying
≤2.0%
1.40%
Ethanol residue
≤0.5%
0.01%
Residue on ignition
≤0.1%
0.085%
Heavy Metal
≤10ppm
Conforms




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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

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