2017年3月8日星期三

Intelectol

Vinpocetine (brand names: Cavinton, Intelectol; chemical name: ethyl apovincaminate) is a synthetic derivative of the vinca alkaloid vincamine (sometimes described as "a synthetic ethyl ester of apovincamine"), an extract from the lesser periwinkle plant. Vinpocetine was first isolated from the plant in 1975 by the Hungarian chemist Csaba Szántay. The mass production of the synthetic compound was started in 1978 by the Hungarian pharmaceutical company Richter Gedeon.
Vinpocetine is not FDA approved in the United States for therapeutic use. The U.S. Food & Drug Administration (FDA) has ruled that vinpocetine, due to its synthetic nature and proposed therapeutic uses, was ineligible to be marketed as dietary supplement under the Federal Food, Drug, and Cosmetic Act (FDCA).
Vinpocetine has been reported to have cerebral blood-flow enhancing and neuroprotective effects, and has been used as a drug in Eastern Europe for the treatment of cerebrovascular disorders and age-related memory impairment.
Name: Vinpocetine
CAS: 42971-09-5
Quality Standard: USP/BP/EP/JP
Apperance: White crystalline power
Specification
ItemsRequirementsResults
AppearanceW  White or slightly yellow, crystalline powder.Complies
Solubility
Practically insoluble in water, soluble in methylene
chl  chloride, slightly soluble in anhydrous ethanol
Complies
Identification
  1. A. Specific optical ration
Should be positiveComplies
  1. B. Infrared absorption
Should be positiveComplies
  1. C. HPLC
The retention time of the main peak of the sample
solution corresponds to that of the principal peak
for the stock standard solution, as obtained in the
test for organic impurities
Complies
Test
  1. A. Specific optical ration
+ 127 ° to + 134°(dried substance)+ 132.4°
  1. B. Related substances
Impurity A≤0.6%
Impurity B≤0.5%
Impurity C≤0.3%
Impurity D≤0.5%
Any other impurities≤0.1%
Total impurities ≤1.0%
0.06%
0.30%
0.06%
NA
0.06%
0.48%
  1. C. Loss on drying
≤ 0.5%0.19%
  1. D. Sulphated ash
≤ 0.1%0.05%
  1. E. Heavy metals
NMT10ppmComplies
Assay98.5%~101.5%99.4%
ConclusionThe product conforms to EP7
PACKING & SHIPING
Delivery time:In 3-5 days
Shipping methods:By Courier, by air or by sea
Packaging: 1kg, 5kg ,25kg or as requested

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