Ilaprazole (trade name Noltec) is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. It is available in strengths of 5, 10, and 20 mg.
Clinical studies show that ilaprazole is at least as potent a PPI as omeprazole when taken in equivalent doses. Studies also showed that ilaprazole significantly prevented the development of reflux oesophagitis.
Ilaprazole is developed by Il-Yang Pharmaceutical (Korea), and is still under clinical trials with US FDA. It has launched in Korea and China for the treatment of gastric ulcer, duodenal ulcer, gastroesophageal reflux disease and erosive esophagitis.
Product Description:
1)Product Name:Supply Fresh 99% Ilaprazole for Proton Pump Inhibitors with cas. 172152-36-2
2)CAS:172152-36-2
3)Molecular Formula:C19H18N4O2S
4)Molecular Weight:366.44
5)Assay:99%
6)Appearance:White or colourless crystalline powder with characteristic odor
Specification:
| Test items | Standard | Imported Drug Registration Standard | |
| Characters | White to pale yellowish white powder. | White to pale yellowish white powder. | |
| Solubility | It is very soluble in water, and freely soluble in ethanol. | Very soluble in water and methanol, freely soluble in ethanol, practically insoluble in ether. | |
Identification
| UV |
Both spectra exhibit similar intensities of
absorption at the same wavelengths
| It exhibits maximum absorption at the wavelength of 292nm. |
| IR |
Both spectra exhibit
similar intensities of absorption at the same wave numbers
|
Both spectra exhibit
similar intensities of absorption at the same wave numbers
| |
Sodium Salt
Reaction
|
A solution of Rabeprazole Sodium (1 in 10) responds
to the Qualitative Tests <1.09>for sodium salt.
| It responds to the Qualitative Tests for sodium salt. | |
| Chromogenic reaction | The solution turns to orange. | ||
| Heavy metals | Not more than 10ppm | Not more than 10ppm | |
| Color and clarity of solution | Not darker than Reference Solution H. | ||
| Related substances |
Individual impurity <0.1%
Total impurities < 1.0%
|
Total impurities < 1.5%
| |
| Loss on drying | Not more than 1.0% | Not more than 1.0% | |
| Residual solvents |
Dichloromethane<600ppm
Acetone < 5000ppm
Ethyl Acetate < 5000ppm
Anhydrous alcohol<5000ppm
|
Dichloromethane < 600ppm
Acetone < 5000ppm
Ethyl Acetate < 5000ppm
Anhydrous alcohol < 5000ppm
| |
| Assay | 98.0%-101.0% | Not less than | |
Packaging & Shipping:
1• Packaging Detail: 100/bag,500g/bag,1kg/bag,25kg/drum
Delivery Detail: According the quantity(Small order:3-5days; Big order:5-15days)
2• Payment terms: T/T 100% in advance by Western union & Company bank account and Paypal(small sample only)
3• Payment way: We accept payments throught Telex transfer, Paypal, Western Union...
4• Shipping methods: We offer several delivery services to suit all customer needs. By Courier or Air and Sea, such as: DHL, FEDEX, TNT, UPS, EMS.
没有评论:
发表评论