Palbociclib (codenamed PD-0332991, trade name Ibrance) is a drug for the treatment of ER-positive and HER2-negative breast cancer developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
Mechanism of action
It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
1 Basic information:
Palbociclib
CAS 571190-30-2
| CAS 571190-30-2 | Brand: Renyoung |
MF C24H29N7O2 | Molecular Weight: | |
Min order: 10grams | ||
Product Categories: | Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fin e Chemicals. | |
Usage | A cyclin-dependent kinase (CDK) inhibitor | |
Standard | Purity:>99% | |
Appearance | White Crystal powder | |
Shelf life | 2 years | |
Storage | Palbociclib should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
2. COA
Items
|
Specifications
|
Results
| |
Appearance
|
A white or off white crystalline powder
|
White crystalline powder
| |
Solubility
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Freely soluble in chloroform
|
Conform
| |
Specific rotation(0)[α]D20
|
+75~+84
|
+78.6
| |
Loss on drying(%)
|
≤1.0
|
0.73
| |
Residue on ignition(%)
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≤0.1
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0.03
| |
Heavy metals(ppm)
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≤20
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conform
| |
Metling point()
|
178-193 centi-degree
|
186-190centi-degree
| |
Purity(HPLC,%)
|
≥98.0
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99.6%
| |
Related substances(HPLC)
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Single impurity: ≤0.5%
Total impurity: ≤1.0%
|
Conform
|
3. Usage:
For Breast cancer treatment or as pharmaceutical intermediates.
4. Packaging & Shipping:
Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 3 days when get the payment
Shipping :
We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR
my contact infomation is:
Email: bettyapi1989@yahoo.com
bettyapi1989@163.com
Skype: bettyapi1989
whatapp: 008613739707029
Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body
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